Use-Dependent Exaggeration of Neuronal Injury after Unilateral Sensorimotor Cortex Lesions
نویسندگان
چکیده
منابع مشابه
Use-dependent exaggeration of neuronal injury after unilateral sensorimotor cortex lesions.
Unilateral injury to the forelimb representation area of the sensorimotor cortex (FL-SMC) in adult rats causes over-reliance on the unimpaired forelimb for postural-motor movements, as well as overgrowth of layer V pyramidal cell dendrites in the homotopic cortex of the noninjured hemisphere. The overgrowth appears to be use-dependent because it can be prevented by restricting movements of the ...
متن کاملMultiple synapse formation in the motor cortex opposite unilateral sensorimotor cortex lesions in adult rats.
Unilateral damage to the forelimb region of the sensorimotor cortex (FLsmc) in adult rats has previously been found to result in dendritic growth and synaptogenesis in layer V of the contralateral motor cortex. The neuronal growth appears to be mediated in part by lesion-induced changes in the use of the forelimbs. Whether these neuronal changes involve alterations in the structure and/or confi...
متن کاملMotor skill training, but not voluntary exercise, improves skilled reaching after unilateral ischemic lesions of the sensorimotor cortex in rats.
BACKGROUND AND PURPOSE Exercise and rehabilitative training each have been implicated in the promotion of restorative neural plasticity after cerebral injury. Because motor skill training induces synaptic plasticity and exercise increases plasticity-related proteins, we asked if exercise could improve the efficacy of training on a skilled motor task after focal cortical lesions. METHODS Femal...
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Past studies have experienced difficulty in achieving graft survival and behavioural recovery after sensorimotor cortex lesions. In the present work, adult female rats trained preoperatively to cross a narrow beam for food reward were maintained in standard group cages or an enriched environment, commencing one week after a unilateral lesion. One month post-lesion, half of these rats received m...
متن کاملIschemic Sensorimotor Cortex Lesions in Rats
http://nnr.sagepub.com/content/early/2007/12/11/1545968307308551 The online version of this article can be found at: DOI: 10.1177/1545968307308551 published online 11 December 2007 Neurorehabil Neural Repair Monica A. Maldonado, Rachel P. Allred, Erik L. Felthauser and Theresa A. Jones Ischemic Sensorimotor Cortex Lesions in Rats Motor Skill Training, but not Voluntary Exercise, Improves Recove...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1996
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.16-15-04776.1996